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Table 2 Functional classification of porcine follicular fluid proteomes during follicle development Molecular function category

From: Proteome changes of porcine follicular fluid during follicle development

GO terms ~ GO names

Number of annotations per follicle developmental stage, %

Shared proteins

SNA

MNA

LNA

n, %

GO:0005488 ~ Binding

365, 24.0

385, 24.7

408, 24.7

63, 24.0

GO:0005515 ~ Protein binding

178, 11.7

190, 12.2

203, 12.3

32, 12.2

GO:0003674 ~ Molecular function

175, 11.5

182, 11.7

200, 12.1

40, 15.3

GO:0003824 ~ Catalytic activity

143, 9.4

146, 9.4

152, 9.2

22, 8.4

GO:0016787 ~ Hydrolase activity

117, 7.7

114, 7.3

126, 7.6

20, 7.6

GO:0016740 ~ Transferase activity

105, 6.9

102, 6.5

99, 6.0

13, 5.0

GO:0003676 ~ Nucleic acid binding

103, 6.8

105, 6.7

107, 6.5

12, 4.6

GO:0005215 ~ Transport activity

55, 3.6

43, 2.8

42, 2.5

13, 5.0

GO:0016301 ~ Kinase activity

50, 3.3

45, 2.9

38, 2.3

6, 2.3

GO:0015075 ~ Ion transmembrane transporter activity

43, 2.8

31, 2.0

31, 1.9

4, 1.5

GO:0030234 ~ Enzyme regulator activity

41, 2.7

42, 2.7

46, 2.8

23, 8.8

GO:0016491 ~ Oxidoreductase activity

29, 1.9

29, 1.9

33, 2.0

3, 1.1

GO:0005198 ~ Structural molecular activity

27, 1.8

36, 2.3

43, 2.6

7, 2.7

GO:0004872 ~ Signaling receptor activity

24, 1.6

45, 2.9

42, 2.5

2, 0.8

GO:0015267 ~ Channel activity

23, 1.5

18, 1.2

15, 0.9

3, 1.1

GO:0003774 ~ Motor activity

10, 0.7

11, 0.7

19, 1.1

1, 0.4

GO:0016829 ~ Lyase activity

10, 0.7

7, 0.4

10, 0.6

1, 0.4

GO:0016209 ~ Antioxidant activity

7, 0.5

6, 0.4

5, 0.3

1, 0.4

GO:0016853 ~ Isomerase activity

7, 0.5

5, 0.3

6, 0.4

GO:0016874 ~ Ligase activity

7, 0.5

8, 0.5

13, 0.8

1, 0.4

GO:0004386 ~ Helicase activity

2, 0.1

6, 0.4

5, 0.3

GO:0009055 ~ Electron transfer activity

1, 0.1

1, 0.1

6, 0.4

GO:0045182 ~ Translation regulator activity

1, 0.1

1, 0.1

2, 0.1

Total annotation

1523, 100

1559, 100

1654, 100

262, 100

  1. SNA Small non-atretic follicle (< 4 mm), MNA Medium non-atretic follicle (4–6 mm), LNA Large non-atretic follicle (> 6–12 mm)