Fig. 2

Correlations between serum and liver metabolites that were altered by L. frumenti administration. a, b Correlation heat maps for the metabolites in each tissue. The correlation coefficient (rho) is shown in red (positive) or blue (negative) (LF, L. frumenti). c Number of significantly different metabolite correlations between the L. frumenti and PBS groups. d, e Graphical representation of the significant metabolite correlations. Each ribbon indicates a significant correlation between or within each metabolite class and the ribbon thickness represents the number of significantly correlated metabolites. The metabolites were ordered according to metabolite class, as indicated by the colored bar around the circumference