Skip to main content

Table 4 Associations of haplotype blocks with milk production traits in two lactations in Chinese Holstein (LSM ± SE)

From: Identification of single nucleotide polymorphisms of PIK3R1 and DUSP1 genes and their genetic associations with milk production traits in dairy cows

Block

Lactation

Haplotype combination (n)

Milk yield, kg

Fat yield, kg

Fat percentage, %

Protein yield, kg

Protein percentage, %

PIK3R1

1

H1H1 (130)

10,360 ± 89.61bc

343.34 ± 3.81ab

3.33 ± 0.04

304.19 ± 2.78abcd

2.94 ± 0.01Aa

H1H2 (144)

10,048 ± 84.93Aa

337.91 ± 3.63a

3.38 ± 0.03

298.02 ± 2.64Aa

2.97 ± 0.01abc

H1H3 (192)

10,187 ± 79.12ac

336.9 ± 3.41Aa

3.33 ± 0.03

300.14 ± 2.49ACa

2.95 ± 0.01Aac

H1H4 (130)

10,474 ± 86.18Bb

350.09 ± 3.68Bb

3.36 ± 0.04

312.38 ± 2.68Bb

2.99 ± 0.01bc

H2H3 (124)

10,238 ± 87.58abc

335.93 ± 3.73Aa

3.3 ± 0.04

301.63 ± 2.72ACDacd

2.95 ± 0.01ac

H2H4 (65)

10,327 ± 109.41abc

346.65 ± 4.57ab

3.37 ± 0.04

310.8 ± 3.33BCbd

3.01 ± 0.02Bb

H3H3 (68)

10,150 ± 107.13abc

335.16 ± 4.49a

3.32 ± 0.04

299.42 ± 3.27ACDad

2.95 ± 0.02abc

H3H4 (111)

10,448 ± 93.43Bbc

347.85 ± 3.97ab

3.35 ± 0.04

310.36 ± 2.89BDbc

2.98 ± 0.01abc

P value

<.0001

0.0002

0.4417

<.0001

0.0002

2

H1H1 (96)

11,118 ± 100.05Aa

390.74 ± 4.23

3.53 ± 0.04a

328.3 ± 3.08Aa

2.96 ± 0.01ab

H1H2 (106)

10,643 ± 95.67Bb

392.23 ± 4.06

3.69 ± 0.04b

315.26 ± 2.96Bb

2.97 ± 0.01ab

H1H3 (126)

11,056 ± 91.29Aa

395.21 ± 3.9

3.58 ± 0.04ab

324.96 ± 2.84ab

2.95 ± 0.01a

H1H4 (86)

10,863 ± 100.55ab

395.32 ± 4.26

3.64 ± 0.04ab

322.5 ± 3.11ab

2.98 ± 0.01ab

H2H3 (89)

10,920 ± 98.93ab

393.52 ± 4.19

3.6 ± 0.04ab

325.88 ± 3.05b

2.99 ± 0.01ab

H2H4 (42)

10,915 ± 133.11ab

385.35 ± 5.5

3.52 ± 0.05ab

328.33 ± 4.01ab

3.01 ± 0.02b

H3H3 (52)

10,841 ± 124.39ab

388.26 ± 5.19

3.6 ± 0.05ab

321.81 ± 3.78ab

2.97 ± 0.02ab

H3H4 (73)

10,726 ± 110.54ab

387.3 ± 4.64

3.6 ± 0.04ab

319.54 ± 3.38ab

2.99 ± 0.02ab

P value

0.0006

0.4862

0.0305

0.003

0.0142

DUSP1

1

H1H1 (136)

10,202 ± 87.64ab

333.67 ± 3.74

3.29 ± 0.04

301.78 ± 2.72ab

2.96 ± 0.01ab

H1H2 (240)

10,309 ± 73.31ab

343.11 ± 3.19

3.35 ± 0.03

303.68 ± 2.32ab

2.95 ± 0.01ab

H1H3 (241)

10,235 ± 74.22ab

339.15 ± 3.22

3.34 ± 0.03

300.48 ± 2.34Aa

2.94 ± 0.01Aa

H2H2 (112)

10,261 ± 90.23ab

338.92 ± 3.83

3.33 ± 0.04

305.83 ± 2.79ab

2.99 ± 0.01Bb

H2H3 (238)

10,203 ± 73.37a

341.72 ± 3.19

3.38 ± 0.03

301.47 ± 2.33a

2.96 ± 0.01ab

H3H3 (79)

10,526 ± 104.21b

344.29 ± 4.37

3.29 ± 0.04

311.35 ± 3.18Bb

2.96 ± 0.01ab

P value

0.0364

0.0678

0.109

0.0054

0.0131

2

H1H1 (101)

11,043 ± 98.24ADa

402.02 ± 4.16Aa

3.66 ± 0.04

329.32 ± 3.03ACa

2.97 ± 0.01

H1H2 (165)

10,632 ± 82.2Bb

384.09 ± 3.55BCb

3.62 ± 0.03

316.74 ± 2.59BDd

2.97 ± 0.01

H1H3 (156)

10,995 ± 82.56Aa

398.32 ± 3.55Aa

3.62 ± 0.03

327.79 ± 2.58Aa

2.98 ± 0.01

H2H2 (77)

10,248 ± 106.51Cc

376.09 ± 4.48Bb

3.65 ± 0.04

306.23 ± 3.26Bb

2.98 ± 0.01

H2H3 (167)

10,798 ± 82.69ab

395.31 ± 3.57ACa

3.66 ± 0.03

321.26 ± 2.6ADad

2.97 ± 0.01

H3H3 (59)

11,485 ± 118.31Dd

408.46 ± 4.93Aa

3.57 ± 0.05

341.32 ± 3.6Cc

2.97 ± 0.02

P value

<.0001

<.0001

0.4432

<.0001

0.9643

  1. Note: H means haplotype; the number in the bracket represents the number of cows for the corresponding haplotype combination; PIK3R1: H1 (GCTTTA), H2 (GTATTG)), H3 (ATACCG), H4 (GCTTTG), and H5 (GTATTA); DUSP1: H1 (CCGG), H2 (CCGT), and H3 (GTAT); P value shows the significance for genetic effects among the haplotype blocks; a, b, c, d within the same column with different superscripts means P value < 0.05; A, B, C, D within the same column with different superscripts means P value < 0.01