Fig. 2

Dual-luciferase activity assay. a Sketches of recombinant plasmids with rs207593520 (T/G) in the 5′ flanking region of DUSP1 gene. Underlined nucleotides represent the transcription factor binding site sequences of MYBL1 or KLF12 (in blue), and the nucleotide in red was the SNP. b Luciferase activity analysis of the recombinant plasmids in HEK 293 T cells. PGL4.14 was the empty vector, Blank was the blank cell, and *** P value < 0.0001