Putrescine mitigates intestinal atrophy through suppressing inflammatory response in weanling piglets

Table 4 The concentrations of polyamines in culture medium and cells treated with putrescine or DFMO

Item	Ctrl	DFMO	DFMO+Put	Put	SEM	P-value
Medium polyamines, nmol/mL
Putrescine	0.26^c	0.15^c	136.67^a	111.33^b	18.87	< 0.01
Spermidine	3.84^a	1.82^b	1.79^b	2.33^b	0.29	< 0.01
Spermine	29.33^c	37.33^b	51.67^a	50.00^a	2.86	< 0.01
Cell lysates polyamines, nmol/mL
Putrescine	1.87^b	0.66^c	2.61^a	2.54^a	0.25	< 0.01
Spermidine	12.21^a	4.46^b	11.31^a	11.35^a	0.96	< 0.01
Spermine	10.78^b	11.38^b	16.09^a	14.88^a	0.70	< 0.01

Note: n = 4. Ctrl control, DFMO 5 mmol/L difluoromethyl ornithine, Pu, 200 μmol/L putrescine;
^a-c Within a row, means not sharing the same superscript differ (P < 0.05)

ISSN: 2049-1891