Single nucleotide polymorphisms in candidate genes are significantly associated with resistance to Haemonchus contortus infection in goats

Table 1 Least-square means and standard errors for log-transformed fecal egg count, body weight, and packed cell volume for goats exposed to natural infection with H. contortus in China and Bangladesh

Main effect	Class	No.	LFEC (log₁₀)		Body weight, kg		PCV, %
Main effect	Class	No.	Mean ± SE	Max.	Mean ± SE	Range	Mean ± SE	Range
China
Location	Yichang	182	2.34 ± 0.05^a	15,600	26.13 ± 0.2.3	6 to 33	17.08 ± 0.48	17 to 35
	Enshi	98	2.45 ± 0.06^b	9400	25.83 ± 0.32	8 to 36	17.68 ± 0.66	17 to 33
			ns		ns		ns
Breed	YCW	32	2.25 ± 0.11^a	2400	26.15 ± 0.57	6 to 28	18.72 ± 0.98^b	18 to 33
	NJY	56	2.08 ± 0.08^b	5400	25.92 ± 0.42	6 to 32	17.96 ± 0.86^c	17 to 32
	ESB	37	2.53 ± 0.10^a	3600	26.27 ± 0.52	9 to 36	20.35 ± 0.99^a	18 to 33
	Chinese crossbred	155	2.48 ± 0.05^c	15,600	25.83 ± 0.25	6 to 33	17.99 ± 0.52^c	18 to 35
			***		ns		*
Bangladesh
Breed	BBG	227	1.58 ± 0.04	400	26.53 ± 0.21	6 to 35	20.16 ± 0.43	18 to 35
China & Bangladesh
Sex	Male	151	2.09 ± 0.04^a	15,600	26.30 ± 0.17	6 to 36	17.55 ± 0.37	17 to 35
	Female	356	1.86 ± 0.06^b	7200	26.14 ± 0.26	6 to 35	17.39 ± 0.56	17 to 32
			**		ns		ns

Goats from China and Bangladesh differed (P < 0.001) for LFEC and PCV but not body weight
Fecal egg counts (FEC) were transformed as LFEC = log₁₀ [(FEC + 25)]
SE standard error, PCV packed cell volume, YCW Yichang White, NJY Nanjiang Yellow, ESB Enshi Black, BBG Black Bengal Goat
Significance levels for each main effect and measured variable are shown on the line following the last main effect class. ***: P < 0.001; **: P < 0.01; ns: not significant
^{a, b, c}Means within a country designation and main effect with different superscripts differ (P < 0.05)

ISSN: 2049-1891