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Fig. 3 | Journal of Animal Science and Biotechnology

Fig. 3

From: Revolutionize livestock breeding in the future: an animal embryo-stem cell breeding system in a dish

Fig. 3

A schematic of ESC derivation and in vitro induced gametogenesis. a In vitro induction of functional gametes from ESCs. EpiLCs and PGCLCs are sequentially induced using well-established female or male ESCs. Next, via aggregation with fetal or neonatal gonadal somatic cells under in vitro conditions, in vitro–derived PGCLCs are successfully converted into primary spermatocytes/oocytes respectively, which are further induced into functional haploid sperm and oocytes. b Derivation and establishment of pluripotent ESC lines from inner cellular mass (ICM) frim in vitro cultured blastocysts

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