Effects of dietary Clostridium butyricum supplementation on growth performance, intestinal development, and immune response of weaned piglets challenged with lipopolysaccharide

Table 7 Effect of C. butyricum (CB) supplementation on plasma cytokine concentrations of weaned pigs challenged with LPS^c

Items		–LPS		+LPS		SEM	P-value
Items		CON	CB	CON	CB	SEM	CB	LPS	Time	CB × LPS	CB × Time	LPS × Time	CB × LPS × Time
IL-6, ng/L	0 h	222.99	204.67	220.53	208.16	3.511	0.235	0.064	0.268	0.303	0.391	0.418	0.480
	2 h	209.61	200.82	239.33	216.21
	4 h	207.11	230.70	243.49	230.91
	Average	213.24	212.06	234.45	218.43
TNF-α, ng/L	0 h	211.27	245.28	253.01	239.81	4.384	0.471	0.063	0.213	0.038	0.308	0.973	0.94
	2 h	231.11	240.78	268.07	242.16
	4 h	250.86	246.20	282.36	243.80
	Average	231.08^b	244.09^ab	267.812^a	241.92^ab

^{a, b}Means in the same row with different superscript letters differ significantly (P < 0.05)
^cCON, piglets fed the basal diet; CB, piglets fed the basal diet supplemented with 0.4% C. butyricum preparation; −LPS, piglets not challenged with LPS; +LPS, piglets challenged with LPS

ISSN: 2049-1891