Fig. 3

Topology analysis of metabolic pathways identified among the feeding, 24Â h fasting and 48Â h fasting comparisons. The X-axis represents the pathway impact, and Y-axis represents the pathway enrichment. Larger sizes and darker colors represent greater pathway enrichment and higher pathway impact values, respectively. I: Linoleic acid metabolism; II: Arginine and proline metabolism; III: Sphingolipid metabolism; IV: Alanine, aspartate and glutamate metabolism; V: Pantothenate and CoA biosynthesis