Effects of Lactobacillus acidophilus on the growth performance and intestinal health of broilers challenged with Clostridium perfringens

Table 8 Cytokine mRNA expression levels in the spleen of broilers at d 21 (log₂ relative)

Item	IL-1 β	IL-8	IFN-γ	TNF-α	IL-10
CTL	1.03	1.02^b	1.04	1.00	1.15
LA	0.90	1.09^b	0.98	0.92	1.32
CLG	1.29	1.30^a	1.25	1.22	0.88
CLG + LA	1.08	1.03^b	1.13	0.94	1.38
SEM	0.046	0.039	0.043	0.034	0.118
Main effects
C. perfringens challenge
Negative	0.96	1.06	1.01	0.96	1.23
Positive	1.18	1.17	1.19	1.08	1.13
L. acidophilus
No addition	1.16	1.16	1.14	1.11	1.02
Addition	0.99	1.06	1.06	0.93	1.35
P-value
C. perfringens challenge	0.009	0.153	0.039	0.034	0.665
L. acidophilus	0.043	0.118	0.302	0.002	0.180
C. perfringens challenge × L. acidophilus	0.619	0.020	0.758	0.079	0.496

ISSN: 2049-1891