Effects of dietary Bacillus amyloliquefaciens supplementation on growth performance, intestinal morphology, inflammatory response, and microbiota of intra-uterine growth retarded weanling piglets

Table 8 Effects of Bacillus amyloliquefaciens on intestinal immune status of weanling piglets with intra-uterine growth retardation

Items^a		NBW-CON (NC group)	IUGR-CON (IC group)	IUGR-BA (IB group)	SEM	Contrast
Items^a		NBW-CON (NC group)	IUGR-CON (IC group)	IUGR-BA (IB group)	SEM	NC vs. IC	IC vs. IB
Jejunum	TNF-α^b, pg/mg protein	0.90	1.61	0.84	0.13	0.038	0.024
	IFN-γ^b, pg/mg protein	1.52	2.13	1.44	0.13	0.093	0.054
	IL-1β^b, pg/mg protein	4.37	8.56	5.49	0.64	0.011	0.062
	IL-4^b, pg/mg protein	1.26	1.27	1.54	0.08	0.998	0.406
	IL-6^b, pg/mg protein	1.71	3.10	2.34	0.29	0.120	0.495
	IL-10^b, pg/mg protein	19.09	14.40	22.22	1.30	0.227	0.029
	MCP-1^b, pg/mg protein	5.30	7.30	5.88	0.34	0.031	0.140
	MPO^c, IU/g protein	25.24	61.00	29.68	5.25	0.005	0.052
Ileum	TNF-α^b, pg/mg protein	1.20	1.68	1.00	0.10	0.082	0.012
	IFN-γ^b, pg/mg protein	1.93	2.24	1.57	0.15	0.632	0.148
	IL-1β^c, pg/mg protein	6.66	13.78	7.06	1.17	0.092	0.080
	IL-4^b, pg/mg protein	0.79	0.80	1.06	0.06	0.999	0.211
	IL-6^b, pg/mg protein	1.80	1.84	2.03	0.15	0.994	0.872
	IL-10^c, pg/mg protein	22.38	12.30	25.76	1.79	0.028	0.004
	MCP-1^b, pg/mg protein	5.37	8.67	7.17	0.54	0.025	0.394
	MPO^b, IU/g protein	38.41	73.12	49.48	4.59	0.001	0.020

^aIFN-γ interferon gamma, IL-1β interleukin 1 beta, IL-4 interleukin 4; IL-6 interleukin 6, IL-10 interleukin 10, IUGR-BA piglets with intrauterine growth retardation fed the Bacillus amyloliquefaciens-supplemented diet, IUGR-CON piglets with intrauterine growth retardation fed the control diet, MCP-1 monocyte chemotactic protein 1, MPO myeloperoxidase, NBW-CON piglets with normal birth weight fed the control diet, TNF-α tumor necrosis factor alpha
^bOne-way ANOVA test. A value of P < 0.05 was considered as statistically significant
^cNon-parametric Kruskal-Wallis test. A value of P < 0.05 was considered as statistically significant

ISSN: 2049-1891