Fig. 3
From: Primordial germ cell-mediated transgenesis and genome editing in birds
Historical contributions to advancemnet of primordial germ cell-mediated production of germline chimeras and genetic modulation in birds. PGC, primordial germ cell; bPGC, embryonic blood-derived PGC; gPGC, embryonic gonad-derived PGC; HR, homologous recombination; TALEN, transcription activator-like effector nuclease; CRISPR/Cas9, clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR associated protein; HDR, homology-directed repair