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Table 2 Effects of subcutaneous injections of TNFα receptor loop peptide (TRLP)a on plasma metabolites in energy restricted cowsb (n = 5)

From: Effects of TNF receptor blockade on in vitro cell survival and response to negative energy balance in dairy cattle

Itemc

Treatment

 

P-value

Control

TRLP

SEM

TRT

TRT × day

Glucose, mg/dL

59.0

58.5

0.3

0.28

0.98

Insulind, ng/mL

0.42

0.58

0.11

0.14

0.85

BHBA, μmol/L

235

218

16

0.48

0.19

NEFA, μEq/L

409

443

27

0.34

1.00

Haptoglobind, μg/mL

27.6

54.9

12.5

0.27

0.31

RQUICKIe

0.55

0.50

0.03

0.04

0.98

  1. aCows were administered subcutaneous injections of TRLP at 1.75 mg/kg BW per day or carrier (Control) every 4 h for 7 d
  2. bCows were fed a diet restricted to provide 40% of estimated energy requirements for maintenance
  3. cValues at enrollment were used as covariate
  4. dLog10 transformation was used for statistical analysis and back-transformed LS means and SEM are presented
  5. eRevised Quantitative Insulin Sensitivity Check Index, calculated as: 1/ [log(glucose, mg/dL) + log(insulin, μU/L) + log(NEFA, mmol/L)] (Holtenius and Holtenius, 2007)
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Journal of Animal Science and Biotechnology

ISSN: 2049-1891