Fig. 4

Significant KEGG pathways for MAT or SAT fat depots of cows fed HIGH or CON diets. Analysis performed using the Dynamic Impact Approach (DIA) with differentially expressed genes (P value <0.05; FDR < 0.20) using the Kyoto Encyclopedia of Genes and Genomes (KEGG) Pathways database. Flux represents the direction of each category and the corresponding subcategory (green color = inhibition, yellow color = stable, red color = activation with different color intensities according with the level of up-regulation or down-regulation). Blue bars denote the impact of each biological process. MAT: mesenteric adipose tissue; SAT: subcutaneous adipose tissue; HIGH: high energy diet; CON: controlled energy diet