Fig. 2From: Level of dietary energy and 2,4-thiazolidinedione alter molecular and systemic biomarkers of inflammation and liver function in Holstein cowsExpression of genes associated with gluconeogenesis (PC), lipid metabolism nuclear receptors (PPARA), ketogenesis (HMGCS2), hepatokines (ANGPTL4 and FGF21), and inflammation (TNF) in liver tissue of cows fed either a controlled-energy diet (CON, 1.30 Mcal/kg diet dry matter; n = 7) or a moderate-energy diet (OVE, 1.60 Mcal/kg diet dry matter; n = 7) before and during 2,4-thiazolidinedione (TZD) administration. The dotted line denotes the start of TZD infusion on d 15 relative to diet initiation. *Significant (P < 0.05) difference due to diet or Diet × Time. a,bSignificant (P < 0.05) overall difference due to timeBack to article page