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Fig. 2 | Journal of Animal Science and Biotechnology

Fig. 2

From: Level of dietary energy and 2,4-thiazolidinedione alter molecular and systemic biomarkers of inflammation and liver function in Holstein cows

Fig. 2

Expression of genes associated with gluconeogenesis (PC), lipid metabolism nuclear receptors (PPARA), ketogenesis (HMGCS2), hepatokines (ANGPTL4 and FGF21), and inflammation (TNF) in liver tissue of cows fed either a controlled-energy diet (CON, 1.30 Mcal/kg diet dry matter; n = 7) or a moderate-energy diet (OVE, 1.60 Mcal/kg diet dry matter; n = 7) before and during 2,4-thiazolidinedione (TZD) administration. The dotted line denotes the start of TZD infusion on d 15 relative to diet initiation. *Significant (P < 0.05) difference due to diet or Diet × Time. a,bSignificant (P < 0.05) overall difference due to time

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