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Table 5 Effects of early antibiotic intervention on serum biochemical indexes of pigs with different CP level diets1

From: Long-term effects of early antibiotic intervention on blood parameters, apparent nutrient digestibility, and fecal microbial fermentation profile in pigs with different dietary protein levels

Item Low-CP Normal-CP SEM P-value2
Con Ant Con Ant Ant CP Ant × CP
d 77
 Total protein, g/L 62.00 66.21 63.61 70.79 1.67 0.082 0.031 0.643
 Albumin, g/L 17.73b 23.20a 18.04b 19.45b 0.66 <0.001 0.122 0.049
 Globulin, g/L 44.27 43.01 45.57 51.34 1.73 0.553 0.178 0.342
 Glucose, mmol/L 4.39c 5.58a 5.44ab 5.26b 0.14 0.004 0.189 0.002
 Urea, mmol/L 2.12b 2.16b 2.46b 3.26a 0.12 0.003 <0.001 0.003
 Cholesterol, mmol/L 1.87 1.89 1.97 2.09 0.05 0.890 0.223 0.080
 Triglyceride, mmol/L 0.45 0.60 0.63 0.75 0.03 0.039 0.145 0.323
 HDLC, mmol/L 0.77 0.81 0.84 0.88 0.02 0.132 0.651 0.241
 LDLC, mmol/L 1.03 0.99 1.04 1.14 0.04 0.430 0.045 0.603
d 185
 Total protein, g/L 66.62 65.14 65.26 69.34 1.45 0.378 0.342 0.072
 Albumin, g/L 31.60 32.64 33.48 31.78 0.73 0.664 0.489 0.081
 Globulin, g/L 35.02ab 32.50b 31.78b 37.56a 1.56 0.313 0.567 0.022
 Glucose, mmol/L 4.54b 4.88b 5.54a 4.78b 0.12 0.245 0.021 0.011
 Urea, mmol/L 4.38 4.12 5.02 6.04 0.26 0.352 0.004 0.134
 Cholesterol, mmol/L 2.10 1.97 2.15 2.20 0.07 0.793 0.322 0.542
 Triglyceride, mmol/L 0.46 0.45 0.61 0.57 0.03 0.684 0.020 0.743
 HDLC, mmol/L 0.85 0.77 0.91 0.95 0.02 0.593 0.011 0.151
 LDLC, mmol/L 0.99 0.99 1.01 0.91 0.04 0.572 0.712 0.574
  1. HDLC, high density lipoprotein-cholesterol, LDLC, low density lipoprotein–cholesterol
  2. a-cMeans in the same row with different superscripts differ (P < 0.05)
  3. 1The commercial creep feed with or without in-feed antibiotics (50 mg/kg olaquindox, 50 mg/kg oxytetracycline calcium, and 50 mg/kg kitasamycin) was fed to pig from d 7 to d 42. Thereafter, the Con and Ant group were further randomly assigned to provide a normal (20%, 18%, 14% CP from d 42 to d 77, d 77 to d 120, d 120 to d 185, respectively) or low CP diet (16%, 14%, 10% CP from d 42 to d 77, d 77 to d 120, d 120 to d 185, respectively), respectively. 2The P values indicate main effects for antibiotic (Ant), protein level (CP) and their interaction (Ant x CP), respectively