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Table 5 Effect of supplementing AGP, feed enzymes (ENZ) or yeast extract (YE) without or with ENZ on ileum, jejunum and duodenum histomorphology of weaned piglets after 96 h of challenge with E. coli LPS

From: Short-term effect of supplemental yeast extract without or with feed enzymes on growth performance, immune status and gut structure of weaned pigs challenged with Escherichia coli lipopolysaccharide

   LPS treatmentsc   Factoriald Contrast
Itema NCCb AGP CC YE ENZ YE + ENZ SEM Main effect YE Main effect ENZ YE × ENZ NCC vs CC AGP vs CC AGP vs YE AGP vs ENZ AGP vs YE + ENZ
Duodenum, μm
 Villus height 532 493 410 480 520 538 24.7 0.098 0.004 NS 0.002 0.03 NS NS NS
 Crypt depth 322 308 277 305 314 316 13.1 NS NS NS 0.02 NS NS NS NS
 VH:CD 1.65 1.61 1.50 1.58 1.68 1.70 0.088 NS NS NS NS NS NS NS NS
Jejunum, μm
 Villus height 465 400 293 385 385 412 26.3 0.049 0.047 NS <.0001 0.01 NS NS NS
 Crypt depth 277 269 255 275 282 273 13.2 NS NS NS NS NS NS NS NS
 VH:CD 1.70 1.50 1.15 1.40 1.37 1.51 0.092 0.03 0.07 NS 0.0003 0.01 NS NS NS
Ileum, μm
 Villus height 329 323 272 294 308 306 18.8 NS NS NS 0.04 0.07 NS NS NS
 Crypt depth 265 259 244 233 268 249 13.6 NS NS NS NS NS NS NS NS
 VH:CD 1.24 1.26 1.11 1.26 1.17 1.23 0.067 NS NS NS NS NS NS NS NS
  1. a VH:CD villus height/crypt depth; means are averages of at least 15 well oriented villus and crypt columns
  2. b NCC non-challenged control pigs that were fed the basal diet and injected with sterile saline on d 7
  3. cPigs fed the basal diet without any additive (CC challenged control) or with AGP, YE, ENZ or ENZ + YE and injected with E. coli LPS on d 7
  4. d P-value for LPS + ENZ × LPS + YE interaction (CC, YE, ENZ and ENZ + YE)