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Table 5 Effect of supplementing AGP, feed enzymes (ENZ) or yeast extract (YE) without or with ENZ on ileum, jejunum and duodenum histomorphology of weaned piglets after 96 h of challenge with E. coli LPS

From: Short-term effect of supplemental yeast extract without or with feed enzymes on growth performance, immune status and gut structure of weaned pigs challenged with Escherichia coli lipopolysaccharide

  

LPS treatmentsc

 

Factoriald

Contrast

Itema

NCCb

AGP

CC

YE

ENZ

YE + ENZ

SEM

Main effect YE

Main effect ENZ

YE × ENZ

NCC vs CC

AGP vs CC

AGP vs YE

AGP vs ENZ

AGP vs YE + ENZ

Duodenum, μm

 Villus height

532

493

410

480

520

538

24.7

0.098

0.004

NS

0.002

0.03

NS

NS

NS

 Crypt depth

322

308

277

305

314

316

13.1

NS

NS

NS

0.02

NS

NS

NS

NS

 VH:CD

1.65

1.61

1.50

1.58

1.68

1.70

0.088

NS

NS

NS

NS

NS

NS

NS

NS

Jejunum, μm

 Villus height

465

400

293

385

385

412

26.3

0.049

0.047

NS

<.0001

0.01

NS

NS

NS

 Crypt depth

277

269

255

275

282

273

13.2

NS

NS

NS

NS

NS

NS

NS

NS

 VH:CD

1.70

1.50

1.15

1.40

1.37

1.51

0.092

0.03

0.07

NS

0.0003

0.01

NS

NS

NS

Ileum, μm

 Villus height

329

323

272

294

308

306

18.8

NS

NS

NS

0.04

0.07

NS

NS

NS

 Crypt depth

265

259

244

233

268

249

13.6

NS

NS

NS

NS

NS

NS

NS

NS

 VH:CD

1.24

1.26

1.11

1.26

1.17

1.23

0.067

NS

NS

NS

NS

NS

NS

NS

NS

  1. a VH:CD villus height/crypt depth; means are averages of at least 15 well oriented villus and crypt columns
  2. b NCC non-challenged control pigs that were fed the basal diet and injected with sterile saline on d 7
  3. cPigs fed the basal diet without any additive (CC challenged control) or with AGP, YE, ENZ or ENZ + YE and injected with E. coli LPS on d 7
  4. d P-value for LPS + ENZ × LPS + YE interaction (CC, YE, ENZ and ENZ + YE)