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Table 4 The effects of acetylsalicylic acid (ASA) and vitamin E (Vit E) on performance and indices of post-weaning colibacillosis measured for 21 d after weaning in E. coli-infected pigsa

From: Acetylsalicylic acid supplementation improves protein utilization efficiency while vitamin E supplementation reduces markers of the inflammatory response in weaned pigs challenged with enterotoxigenic E. coli

 

ASA (A), ppm

 

Vit E (E), IU

 

P-value

 

0

125

SEM

50

100

200

SEM

A

E

A × E

D 0 – 14

 ADG, g/d

154

173

5.4

175

163

152

5.4

0.034

0.119

0.375

 ADFI, g/d

180

182

5.2

190

181

171

5.2

0.998

0.090

0.503

 G:F

0.87

0.94

0.022

0.93

0.90

0.88

0.022

0.087

0.587

0.175

D 0 – 21

 ADG, g/d

234

245

5.6

250

240

230

5.6

0.218

0.183

0.614

 ADFI, g/d

279

288

6.4

290

280

280

6.4

0.469

0.678

0.867

 G:F

0.86

0.87

0.013

0.87

0.86

0.86

0.013

0.742

0.894

0.412

 Diarrhoea index, %b

8.2

6.0

0.78

7.1

6.4

7.8

0.79

0.126

0.701

0.043

 Antibioticc

1.8

1.7

0.16

1.8

1.8

1.7

0.17

0.724

0.910

0.023

E. coli scored

8.0

6.3

0.79

7.4

5.8

8.2

0.79

0.009

0.002

0.391

  1. aAll pigs were experimentally infected with an enterotoxigenic strain of E. coli on 7, 8 and 9 d after weaning. The numbers of replications were 32 individual pigs up to d 10 and 24 pigs from d 14 to 21
  2. bDiarrhea index, %; mean percentage of days with diarrhea with respect to first 14 d after weaning. Significant interaction (P < 0.05) occurred between ASA and Vit E for the diarrhoea index, such that supplementation of 200 IU Vit E/kg diet decreased diarrhoea index but only with concurrent supplementation of 125 ppm ASA
  3. cMean number of antibiotic treatments. Significant interaction (P < 0.05) occurred between ASA and Vit E for the number of antibiotic treatments, such that supplementation of 200 IU Vit E/kg diet decreased the number of antibiotic treatments but only with concurrent supplementation of 125 ppm ASA
  4. dMean cumulative E. coli scores per diet in the 14 d after weaning