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Table 4 OPLS-DA coefficients derived from the NMR data of metabolites in plasma obtained from different treatments

From: Increased maternal consumption of methionine as its hydroxyl analog promoted neonatal intestinal growth without compromising maternal energy homeostasis

Metabolite Correlation coefficienta
CON-d7 (vs CON-d0) DLM-d7 (vs DLM-d0) HMTBA-d7 (vs HMTBA-d0)
3-Hydroxybutyrate - 0.884 -
Acetamide 0.856 0.796 0.824
Alanine −0.792 - -
Allantoin - −0.757 -
Asparagine - −0.899 -
Betaine - −0.831 -
Choline 0.816 - -
Creatinine −0.902 −0.913 -
Dimethylamine - 0.787 0.843
Glycerol - −0.842 -
Glycerophosphocholine - 0.851 -
Lipid, CH 3-(CH2)n-(LDL) 0.892 0.915 -
Lipid, CH 3-(CH2)n-(VLDL) - 0.859 -
Lipid, CH3-(CH 2)n-(LDL) - 0.837 -
Lipid, =CH-CH 2-CH= - 0.825 -
Lipid, −CH = CH- - 0.886 -
Lysine - −0.822 -
myo-Inositol - −0.874 -
Phenylalanine −0.780 - -
Succinate - −0.785 -
Valine - 0.894 -
α-Glucose - −0.888 -
β-Glucose - −0.853 -
  1. aCorrelation coefficients (r), positive and negative signs indicate positive and negative correlation in the concentrations, respectively. The correlation coefficient of│r│ > 0.755 was used as the cutoff value for the statistical significance based on the discrimination significance at the level of P = 0.05 and df (degree of freedom) = 5. “-” means the correlation coefficient│r│ is less than 0.755. The plasma sample at postpartum d0 of sows fed the control diet (CON-d0), the plasma sample at postpartum d7 of sows fed the DL-methionine diet (CON-d7), the plasma sample at postpartum d0 of sows fed the DL-methionine diet (DLM-d0), the plasma sample at postpartum d7 of sows fed the DL-methionine diet (DLM-d7), the plasma sample at postpartum d0 of sows fed the DL-2-hydroxy-4-methylthiobutanoic acid diet (HMTBA-d0), the plasma sample at postpartum d7 of sows fed DL-2-hydroxy-4-methylthiobutanoic acid diet (HMTBA-d7), low density lipoprotein (LDL), very low density lipoprotein (VLDL)