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Table 4 OPLS-DA coefficients derived from the NMR data of metabolites in plasma obtained from different treatments

From: Increased maternal consumption of methionine as its hydroxyl analog promoted neonatal intestinal growth without compromising maternal energy homeostasis

Metabolite

Correlation coefficienta

CON-d7 (vs CON-d0)

DLM-d7 (vs DLM-d0)

HMTBA-d7 (vs HMTBA-d0)

3-Hydroxybutyrate

-

0.884

-

Acetamide

0.856

0.796

0.824

Alanine

−0.792

-

-

Allantoin

-

−0.757

-

Asparagine

-

−0.899

-

Betaine

-

−0.831

-

Choline

0.816

-

-

Creatinine

−0.902

−0.913

-

Dimethylamine

-

0.787

0.843

Glycerol

-

−0.842

-

Glycerophosphocholine

-

0.851

-

Lipid, CH 3-(CH2)n-(LDL)

0.892

0.915

-

Lipid, CH 3-(CH2)n-(VLDL)

-

0.859

-

Lipid, CH3-(CH 2)n-(LDL)

-

0.837

-

Lipid, =CH-CH 2-CH=

-

0.825

-

Lipid, −CH = CH-

-

0.886

-

Lysine

-

−0.822

-

myo-Inositol

-

−0.874

-

Phenylalanine

−0.780

-

-

Succinate

-

−0.785

-

Valine

-

0.894

-

α-Glucose

-

−0.888

-

β-Glucose

-

−0.853

-

  1. aCorrelation coefficients (r), positive and negative signs indicate positive and negative correlation in the concentrations, respectively. The correlation coefficient of│r│ > 0.755 was used as the cutoff value for the statistical significance based on the discrimination significance at the level of P = 0.05 and df (degree of freedom) = 5. “-” means the correlation coefficient│r│ is less than 0.755. The plasma sample at postpartum d0 of sows fed the control diet (CON-d0), the plasma sample at postpartum d7 of sows fed the DL-methionine diet (CON-d7), the plasma sample at postpartum d0 of sows fed the DL-methionine diet (DLM-d0), the plasma sample at postpartum d7 of sows fed the DL-methionine diet (DLM-d7), the plasma sample at postpartum d0 of sows fed the DL-2-hydroxy-4-methylthiobutanoic acid diet (HMTBA-d0), the plasma sample at postpartum d7 of sows fed DL-2-hydroxy-4-methylthiobutanoic acid diet (HMTBA-d7), low density lipoprotein (LDL), very low density lipoprotein (VLDL)