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Table 4 The relative mRNA abundances of E-cadherin, occludin, ZO-1, integrin, Kv1.1 and Kv1.5 in the jejunal and ileal mucosa of suckling and weaned piglets

From: Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods

Items

Day age

Day post-weaning

SEM

P-value

1

7

14

21

1

3

5

7

Jejunal mucosa

E-cadherin

1.00b

1.42b

1.64b

2.79a

1.55b

0.38c

0.61c

1.10bc

0.056

<0.001

occludin

1.00b

0.62b

1.40b

5.00a

0.63b

0.32c

0.47c

0.79b

0.087

<0.001

ZO-1

1.00b

1.24ab

1.08b

1.30a

1.01ab

0.66c

0.86bc

0.99b

0.093

0.002

integrin

1.00b

1.08ab

1.13ab

1.48a

0.72b

0.62b

1.20ab

0.98ab

0.148

0.012

Kv1.1

1.00b

1.76ab

2.02ab

0.39c

1.89ab

2.48a

1.14b

1.17b

0.160

0.029

Kv1.5

1.00b

2.50ab

3.13ab

3.23ab

3.96a

4.76a

2.77ab

1.53b

0.235

<0.001

Ileal mucosa

E-cadherin

1.00b

1.39b

1.50b

2.55a

0.97bc

0.34c

0.81bc

1.49b

0.081

<0.001

occludin

1.00b

1.15b

2.29a

3.52a

1.00b

0.87b

1.49b

1.78b

0.154

0.029

ZO-1

1.00b

1.80a

0.98b

0.86b

0.74b

0.65b

0.89b

0.90b

0.092

<0.001

integrin

1.00

1.23

0.81

0.99

0.83

0.49

0.65

0.49

0.186

0.251

Kv1.1

1.00d

3.32b

5.27a

2.36bc

4.39ab

2.42bc

1.84c

1.20d

0.206

0.001

Kv1.5

1.00b

2.77a

1.31b

0.95b

1.54b

1.41b

1.69b

1.25b

0.112

<0.001

  1. ZO-1 Zonula occludens, Kv1.1 Potassium voltage-gated channel, shaker-related subfamily, member 1, Kv1.5 Potassium voltage-gated channel, shaker-related subfamily, member 5
  2. The jejunal and ileal mucosa were obtained from 1, 7, 14, 21-d-old suckling piglets and piglets on d 1, 3, 5, 7 post-weaning at 14 d of age
  3. n = 8. a-dValues with different letters within the same row are different (P < 0.05)