Table 2 Summary of similarities and differences between HMC and TC
From: Handmade cloning: recent advances, potential and pitfalls
S.No. | Features | TC | HMC |
|---|---|---|---|
1. | Somatic cell nuclear transfer | ✓ | ✓ |
2. | Synchronization of donor cell | ✓ | ✓ |
3. | High no. of attempts | ✓ | ✓ |
4. | Problems associated with nuclear reprogramming and reproducibility of experiments | ✓ | ✓ |
5. | True clone | × | × |
6. | Micromanipulator-free | × | ✓ |
7. | Zona- free | × | ✓ |
8. | Problems associated with zona pellucida removal | × | ✓ |
9. | Number of cytoplast required | Lower | Higher |
10. | Costs | Higher | Lower than TC |