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Table 2 Summary of similarities and differences between HMC and TC

From: Handmade cloning: recent advances, potential and pitfalls

S.No. Features TC HMC
1. Somatic cell nuclear transfer
2. Synchronization of donor cell
3. High no. of attempts
4. Problems associated with nuclear reprogramming and reproducibility of experiments
5. True clone × ×
6. Micromanipulator-free ×
7. Zona- free ×
8. Problems associated with zona pellucida removal ×
9. Number of cytoplast required Lower Higher
10. Costs Higher Lower than TC