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Table 1 Expression (FPKM) of SLC genes by short cuboidal and tall columnar trophoblast epithelial cells (see Figure 2 ) from pig placenta collected on day 85 of gestation by laser capture microdissection (n = 4 pigs)

From: Placental accommodations for transport and metabolism during intra-uterine crowding in pigs

Gene Substrate Name P value SC versus TC Short cuboidal Tall columnar
SLC1A3 Amino Acid solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.008342 103.518 152.46*
SLC1A5 Amino Acid solute carrier family 1 (neutral amino acid transporter), member 5 0.005574 19.865 29.593*
SLC2A10 Glucose solute carrier family 2 (facilitated glucose transporter), member 10 0.356081 1.774 2.437
SLC2A12 Glucose solute carrier family 2 (facilitated glucose transporter), member 12 0.019601 93.214 124.979*
SLC2A13 Inositol solute carrier family 2 (facilitated glucose transporter), member 13 0.012995 38.491* 26.879
SLC2A4 Glucose solute carrier family 2 (facilitated glucose transporter), member 4 0.04111 3.39* 2.185
SLC3A1 Amino Acid solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1 0.676755 29.255 28.814
SLC4A1AP None solute carrier family 4 (anion exchanger), member 1, adaptor protein 0.510953 3.625 3.356
SLC4A4 Bicarbonate solute carrier family 4, sodium bicarbonate cotransporter, member 4 0.40478 3.657 2.806
SLC4A7 Bicarbonate solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0625 3.787 2.531
SLC5A6 Vitamins solute carrier family 5 (sodium-dependent vitamin transporter), member 6 2.08E-05 27.352* 7.827
SLC6A6 Amino Acid solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.700481 3.691 4.132
SLC6A8 Creatine solute carrier family 6 (neurotransmitter transporter, creatine), member 8 0.0925 3.97 2.598
SLC7A2 Amino Acid solute carrier family 7 (cationic amino acid transporter, y + system), member 2 0.35208 2.194 1.559
SLC7A4 Amino Acid? solute carrier family 7 (orphan transporter), member 4 0.612879 101.015 99.302
SLC7A7 Amino Acid solute carrier family 7 (amino acid transporter light chain, y + L system), member 7 0.048306 3.179* 2.013
SLC7A8 Amino Acid solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.092703 6.23 4.956
SLC7A9 Amino Acid solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9 0.004643 2.419* 4.289
SLC9A1 Na+/H+ solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.462724 2.827 3.147
SLC9A3R1 Na+/H+ solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 4.51E-05 22.04* 10.738
SLC9A6 Na+/H+ solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.577227 3.025 3.173
SLC9A8 Na+/H+ solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.195039 5.92 4.937
SLC9A9 Na+/H+ solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.109026 4.589 6.648
SLC10A7 steroids solute carrier family 10 (sodium/bile acid cotransporter family), member 7 0.226002 2.569 3.55
SLC12A6 K+/Cl- solute carrier family 12 (potassium/chloride transporters), member 6 0.717437 6.458 6.382
SLC13A3 Dicarboxylate solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.004193 19.292* 28.657
SLC13A4 Sulfate solute carrier family 13 (sodium/sulfate symporters), member 4 1.73E-06 91.288* 44.882
SLC14A1 Urea solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.579099 3.759 5.211
SLC15A1 Di/tripeptides solute carrier family 15 (oligopeptide transporter), member 1 0.10901 2.251 1.715
SLC15A2 Di/tripeptides solute carrier family 15 (H+/peptide transporter), member 2 6.49E-05 84.452 147.72*
SLC16A10 Amino Acid solute carrier family 16, member 10 (aromatic amino acid transporter) 0.057011 47.966 38.846
SLC16A12 Creatine solute carrier family 16, member 12 (monocarboxylic acid transporter 12) 5.09E-05 7.95* 2.177
SLC16A14 ? solute carrier family 16, member 14 (monocarboxylic acid transporter 14) 0.002365 9.309* 5.651
SLC16A7 Lactate solute carrier family 16, member 7 (monocarboxylic acid transporter 2) 0.01361 3.627* 1.939
SLC16A9 Urate solute carrier family 16, member 9 (monocarboxylic acid transporter 9) 0.348855 3.476 2.655
SLC17A5 Acid sugars solute carrier family 17 (anion/sugar transporter), member 5 0.627423 7.041 7.408
SLC19A2 Thiamine solute carrier family 19 (thiamine transporter), member 2 0.009728 3.455* 2.193
SLC20A1 Phosphate solute carrier family 20 (phosphate transporter), member 1 0.003578 8.612* 4.872
SLC22A18 Organic cations solute carrier family 22, member 18 0.12071 2.883 1.365
SLC22A23 ? solute carrier family 22, member 23 0.396248 3.315 3.06
SLC22A3 Polyamines solute carrier family 22 (extraneuronal monoamine transporter), member 3 0.000145 3.563* 0.81
SLC25A1 Mitochondrial citrate, malate solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.347209 20.091 17.097
SLC25A11 Mitochondrial oxoglutarate, malate solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.108779 5.333 3.636
SLC25A12 Mitochondrial Amino Acid solute carrier family 25 (aspartate/glutamate carrier), member 12 0.131405 7.194 5.996
SLC25A13 Mitochondrial Amino Acid solute carrier family 25 (aspartate/glutamate carrier), member 13 0.409356 17.13 15.642
SLC25A14 Mitochondrial H+ (uncoupling) solute carrier family 25 (mitochondrial carrier, brain), member 14 0.706134 1.957 2.11
SLC25A17 Mitochondrial CoA, FAD solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34 kDa), member 17 0.721955 7.931 8.946
SLC25A20 Mitochondrial carnitine solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.536736 18.412 20.059
SLC25A24 Mitochondrial ATP solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.345305 12.014 10.704
SLC25A25 Mitochondrial ATP solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 0.219067 1.837 2.319
SLC25A26 Mitochondrial adenosyl-methionine solute carrier family 25 (S-adenosylmethionine carrier), member 26 0.458853 1.883 1.809
SLC25A27 Mitochondrial H+ (uncoupling) solute carrier family 25, member 27 0.050934 3.482* 2.227
SLC25A28 Mitochondrial iron solute carrier family 25 (mitochondrial iron transporter), member 28 0.398812 2.266 1.939
SLC25A3 Mitochondrial phosphate solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.465844 207.118 195.026
SLC25A32 Mitochondrial folate solute carrier family 25 (mitochondrial folate carrier), member 32 0.342663 2.325 3.289
SLC25A33 Mitochondrial UTP solute carrier family 25 (pyrimidine nucleotide carrier), member 33 0.02715 3.591* 1.889
SLC25A36 Mitochondrial UTP solute carrier family 25 (pyrimidine nucleotide carrier), member 36 0.479823 10.419 11.013
SLC25A37 Mitochondrial iron solute carrier family 25 (mitochondrial iron transporter), member 37 0.684822 8.405 8.581
SLC25A43 Mitochondrial ? solute carrier family 25, member 43 0.004424 2.411 4.746*
SLC25A44 Mitochondrial ? solute carrier family 25, member 44 0.660881 4.946 5.013
SLC25A46 Mitochondrial ? solute carrier family 25, member 46 0.714232 3.622 4.053
SLC25A5 Mitochondrial ADP, ATP solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.225204 73.01 94.084
SLC26A2 Sulfate, chloride, hydroxyl ions solute carrier family 26 (sulfate transporter), member 2 0.002566 18.742* 9.657
SLC27A4 Long chain fatty acids solute carrier family 27 (fatty acid transporter), member 4 0.718866 2.528 2.328
SLC27A6 Long chain fatty acids solute carrier family 27 (fatty acid transporter), member 6 0.001938 5.536* 1.159
SLC29A1 Nucleosides solute carrier family 29 (nucleoside transporters), member 1 0.002403 51.871* 28.705
SLC29A3 Nucleosides solute carrier family 29 (nucleoside transporters), member 3 0.0282 4.818* 3.052
SLC30A4 Zinc solute carrier family 30 (zinc transporter), member 4 0.137271 2.308 1.538
SLC30A6 Zinc solute carrier family 30 (zinc transporter), member 6 0.544857 6.784 6.425
SLC30A7 Zinc solute carrier family 30 (zinc transporter), member 7 0.606204 10.946 11.388
SLC30A9 Zinc solute carrier family 30 (zinc transporter), member 9 0.040343 12.638* 9.474
SLC31A2 Copper solute carrier family 31 (copper transporters), member 2 0.692963 3.737 4.636
SLC35A1 Nucleotide sugar solute carrier family 35 (CMP-sialic acid transporter), member A1 0.001966 8.876* 3.703
SLC35A3 Nucleotide sugar? solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.003442 19.107 33.186*
SLC35A4 Nucleotide sugar? solute carrier family 35, member A4 0.717081 2.659 2.795
SLC35A5 Nucleotide sugar? solute carrier family 35, member A5 0.683471 5.015 5.377
SLC35B1 Adenosine phospho-sulfate solute carrier family 35, member B1 0.347209 14.398 13.503
SLC35B2 Adenosine phospho-sulfate solute carrier family 35, member B2 0.53865 2.75 2.625
SLC35B3 Adenosine phospho-sulfate solute carrier family 35, member B3 0.353606 6.322 5.239
SLC35C1 Nucleotide sugar solute carrier family 35, member C1 0.00016 19.1* 6.88
SLC35D1 Nucleotide sugar solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 0.688317 3.286 2.87
SLC35E1 ? solute carrier family 35, member E1 0.066081 4.953 2.826
SLC35E3 ? solute carrier family 35, member E3 0.265752 2.049 1.612
SLC35F2 ? solute carrier family 35, member F2 0.10158 3.188 2.186
SLC35F5 ? solute carrier family 35, member F5 0.289527 22.192 24.888
SLC36A1 Amino acid solute carrier family 36 (proton/amino acid symporter), member 1 0.157349 19.844 16.848
SLC36A4 Amino acid solute carrier family 36 (proton/amino acid symporter), member 4 0.159179 2.836 1.761
SLC37A1 Sugar phosphate solute carrier family 37 (glycerol-3-phosphate transporter), member 1 0.000295 3.492* 1.626
SLC37A4 Sugar phosphate solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.196418 6.082 5.027
SLC38A1 Amino acid solute carrier family 38, member 1 0.023371 11.839* 9.529
SLC38A6 Amino acid? solute carrier family 38, member 6 0.00099 3.834 7.593*
SLC38A7 Glutamine solute carrier family 38, member 7 0.657535 2.284 2.435
SLC38A9 Amino acid? solute carrier family 38, member 9 0.203752 4.997 3.792
SLC39A11 Zinc solute carrier family 39 (metal ion transporter), member 11 0.519439 18.918 20.158
SLC39A14 Zinc, iron, cadmium solute carrier family 39 (zinc transporter), member 14 5.13E-05 19.797* 8.718
SLC39A7 Zinc solute carrier family 39 (zinc transporter), member 7 0.644212 9.946 10.299
SLC39A8 Zinc, cadmium solute carrier family 39 (zinc transporter), member 8 0.219082 6.948 4.375
SLC39A9 Zinc solute carrier family 39 (zinc transporter), member 9 0.029289 12.607* 8.939
SLC44A1 Choline solute carrier family 44, member 1 0.004045 29.547 45.151*
SLC44A2 Choline solute carrier family 44, member 2 0.502802 22.687 21.741
SLC44A3 Choline? solute carrier family 44, member 3 0.014683 6.273 10.268*
SLC44A4 Thiamine pyro-phosphate, choline solute carrier family 44, member 4 0.002671 6.012* 2.58
SLC46A3 Folate? solute carrier family 46, member 3 0.208452 4.484 3.561
SLC47A1 Organic cations (e.g. creatinine) solute carrier family 47, member 1 0.645687 2.158 2.886
SLC47A2 Organic cations (e.g. creatinine) solute carrier family 47, member 2 0.60417 3.179 2.282
SLCO2A1 Prostaglandins solute carrier organic anion transporter family, member 2A1 0.000609 70.11 123.911*
SLCO2B1 Steroids, prostaglandins solute carrier organic anion transporter family, member 2B1 0.004457 3.665* 2.195
SLCO4C1 thyroxin solute carrier organic anion transporter family, member 4C1 1.95E-05 68.57* 36.456
  1. *Asterisk indicates greater expression in cell type indicated (P<0.05).