Figure 2
From: Conceptus elongation in ruminants: roles of progesterone, prostaglandin, interferon tau and cortisol
Schematic illustrating working hypothesis of the biological role of interferon tau (IFNT) and prostaglandins (PGs) in uterine function and conceptus elongation during early pregnancy in sheep. See text for detailed description. Legend: ABCC4, ATP-binding cassette, sub-family C (CFTR/MRP), member 4; CREB, cAMP responsive element binding protein; IFNAR, interferon (alpha, beta and omega) receptor; DP, prostaglandin D receptor (PTGDR); EP, prostaglandin E receptor (PTGER); FP, prostaglandin F receptor (PTGFR); IP, prostaglandin I receptor (PTGIR); PLA2, phospholipase A2; PPARD, peroxisome proliferator-activated receptor delta; PPARG, peroxisome proliferator-activated receptor gamma; PTGS2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); PG Synthases, prostaglandin synthases (AKR1C3, PTGDS, PTGES, PTGFS, PTGIS, TBXAS); SLCO2A1, solute carrier organic anion transporter family, member 2A1 (prostaglandin transporter); TBXA2R, thromboxane A2 receptor.