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Table 4 Gene expression 1 in semitendinosus muscle of CON 2 , OVER or RES lambs

From: Poor maternal nutrition inhibits muscle development in ovine offspring

 

Day 1

3 Months

Gene

CON

OVER

RES

P-value

CON

OVER

RES

P-value

Pax7

1.38 ± 0.67

1.20 ± 0.27

1.86 ± 0.51

0.70

1.14 ± 0.31

1.42 ± 0.24

1.94 ± 0.77

0.46

MyoD

2.16 ± 1.36

3.51 ± 0.90

2.70 ± 0.98

0.88

1.11 ± 0.29

1.01 ± 0.01

1.27 ± 0.29

0.83

Myogenin

1.53 ± 0.74

2.13 ± 0.74

2.65 ± 0.71

0.57

1.21 ± 0.35

1.24 ± 0.47

2.41 ± 0.66

0.24

Myostatin

1.17 ± 0.36

2.94 ± 0.50**

1.63 ± 0.51

0.11

1.02 ± 0.10

1.89 ± 0.26

1.51 ± 0.58

0.36

Follistatin

1.03 ± 0.16

1.92 ± 0.39*

1.73 ± 0.28**

0.09

1.10 ± 0.21

1.56 ± 0.21

1.51 ± 0.34

0.36

Foxo1

1.12 ± 0.30

0.64 ± 0.29

0.74 ± 0.29

0.37

1.06 ± 0.16

0.91 ± 0.36

0.32 ± 0.07*

0.04

Foxo3a

1.60 ± 0.73

0.72 ± 0.26

1.12 ± 0.56

0.70

1.09 ± 0.24

1.42 ± 0.43

0.77 ± 0.14

0.21

  1. 1Relative to CON, mean ± SEM.
  2. 2CON = lambs from control-fed ewes (100% NRC, d 1, n = 4; 3 mo, n = 5), OVER = lambs from overfed ewes (140% NRC, d 1, n = 5; 3 mo, n = 3), RES = lambs from restricted-fed ewes (60% NRC, d 1, n = 6; 3 mo, n = 4).
  3. *P < 0.05 compared with CON.
  4. **P < 0.01 compared with CON.