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Table 2 Gene enrichment analysis of EMMIX Cluster A

From: A gene expression estimator of intramuscular fat percentage for use in both cattle and sheep

Prob1 EMMIX GOrrila
Genes P-value FDR Q-value Genes4 Enrichment5
Total2 Positive2 Negative3
≥0.9 571 121 136 7.66E-13 8.13E-09 30 4.57
≥0.8 768 153 170 8.56E-12 9.09E-08 31 4.12
≥0.7 920 177 198 8.38E-10 2.97E-06 32 3.37
≥0.6 1109 210 237 1.79E-08 3.80E-05 33 2.93
≥0.5 1342 248 282 8.12E-08 1.08E-04 35 2.67
  1. 1Probability of genes to be located in cluster A.
  2. 2Genes with positive coordinates in all three datasets, see Additional file 1: Table S1 sheet “Genes with positive coordinates”.
  3. 3Genes with all negative coordinates in all the three datasets.
  4. 4Number of genes enriched in “lipid metabolic process” GO term from genes with all positive coordinates in all the three datasets.
  5. 5Enrichment (N, B, n, b) is defined as follows: N - is the total number of genes; B - is the total number of genes associated with a specific GO term; n - is the number of genes in the top of the user's input list or in the target set when appropriate; b - is the number of genes in the intersection; Enrichment = (b/n) / (B/N).