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Table 2 Eight-Wk maternal insulin infusion

From: Changes in fetal mannose and other carbohydrates induced by a maternal insulin infusion in pregnant sheep

Measurement Control Hypoglycemic HG+I
Gestational age, d 133.2 ± 1.1 133.0 ± 1.3 134.5 ± 0.9
Maternal plasma arterial carbohydrates, μmol/L
 Glucose 3,605 ± 203 1,715 ± 145** 1,817 ± 95**
 Mannose 67.0 ± 4.3 34.7 ± 3.5** 31.4 ± 5.0**
 Inositol 27.7 ± 4.4 34.9 ± 3.9 34.6 ± 3.1
 Sorbitol 13.4 ± 3.4 18.8 ± 4.2 11.8 ± 1.3
 Erythritol 52.8 ± 5.5 44.5 ± 3.1 39.6 ± 8.5
 Arabinol 96.2 ± 13.3 125.6 ± 6.5 118.0 ± 23.3
 Ribitol 25.6 ± 3.0 25.9 ± 3.2 16.1 ± 4.3
Fetal weight, kg 3.66 ± 0.12 2.20 ± 0.14** 2.61 ± 0.21**
Fetal plasma arterial insulin, ng/mL 0.46 ± 0.09 0.16 ± 0.03* 0.66 ± 0.17
Fetal plasma arterial carbohydrates, μmol/L
 Glucose 1,553 ± 282 587 ± 56** 511 ± 37**
 Mannose 30.4 ± 3.8 17.0 ± 1.1** 7.9 ± 0.9**
 Inositol 741.4 ± 240.8 910.1 ± 157.5 792.2 ± 199.5
 Sorbitol 188.5 ± 31.9 55.2 ± 11.9** 41.3 ± 8.3**
 Fructose 4,508 ± 981 1,631 ± 301** 800 ± 154**
 Erythritol 394.6 ± 30.7 372.2 ± 9.3 311.6 ± 24.6
 Arabinol 235.3 ± 17.1 237.5 ± 15.1 214.9 ± 54.3
 Ribitol 124.3 ± 15.9 139.6 ± 21.7 156.8 ± 57.6
 Mannitol 47.4 ± 8.5 31.4 ± 6.1 33.8 ± 8.7
Fetal hepatic sorbitol and fructose, nmol/g   
 Sorbitol 589.0 ± 90.1 205.8 ± 42.1** 161.3 ± 56.0**
 Fructose 1,679 ± 219 398 ± 119** 215 ± 95**
  1. Values are means ± SEM. *, ** refer to significant differences from Control (n = 5) animals; P < 0.05, 0.01, respectively, by ANOVA.