Changes in fetal mannose and other carbohydrates induced by a maternal insulin infusion in pregnant sheep

Table 1 Two-Wk maternal insulin infusion

Measurement	Control	Hypoglycemic
Gestational age, d	138.5 ± 0.4	137.5 ± 0.8
Fetal weight, kg	4.37 ± 0.14	3.30 ± 0.18**
Fetal plasma arterial insulin, ng/mL	0.30 ± 0.03	0.11 ± 0.01**
Fetal plasma arterial carbohydrates, μmol/L
Glucose	1,159 ± 64	594 ± 47**
Mannose	24.5 ± 1.2	15.9 ± 1.4**
Inositol	638.5 ± 138.6	1,129.0 ± 256.1
Sorbitol	123.8 ± 12.7	53.9 ± 10.5**
Fructose	4771 ± 450	1,909 ± 356**
Erythritol	399.6 ± 28.1	345.9 ± 20.8
Arabinol	245.0 ± 11.9	225.3 ± 15.6
Ribitol	128.1 ± 9.1	148.5 ± 18.8
Mannitol	72.8 ± 9.7	49.8 ± 10.1

Values are means ± SEM. ** refer to significant differences between Control (n = 13) and Hypoglycemic (n = 8); P < 0.01 by Students t test or the Mann–Whitney test.

ISSN: 2049-1891