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Table 3 Quantitative RT-PCR of non-opsonized Salmonella strain Δ pflB::kan during invasion of THP-1 cells

From: Deletions in the pyruvate pathway of Salmonella Typhimurium alter SPI1-mediated gene expression and infectivity

Time post-infection Salmonella gene Expression* Regulation**
1 h No change   
2.5 h invE 1.71 UP
invC −1.46 DOWN
invH −1.41
rtsA −1.70
sicA −1.52
sicP −1.34
sipC −1.36
4 h hilA 1.72 UP
hilD 1.36  
invF 1.19  
prgJ 1.18  
6 h hilA −1.61 DOWN
hilC −1.97
hilD −1.55
invC −1.54
invE −1.51
invF −1.52
invH −1.61
orgA −1.66
orgB −1.30
prgH −1.43
prgJ −1.46
rtsA −1.83
sicA −1.89
sicP −1.63
sipA −1.58
sipB −2.00
sipC −1.70
  1. *Values listed are relative fold-change values as compared to the wild-type strain ATCC 14028; **All genes listed are significant at p-value < 0.05.