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Table 2 Effects of antibiotics or the antimicrobial peptide cecropin on intestinal morphology and intestinal microflora of four week old weaned pigs after challenge with E. coli

From: Alternatives to antibiotics as growth promoters for use in swine production: a review

Items Control Antibiotic1 Cecropin SEM P-value
Intestinal Morphology
 Duodenum
 Villus height, μm 418 439 431 10.7 0.53
 Crypt depth, μm 233 227 232 5.3 0.41
 Villus height to crypt depth ratio 1.83 1.96 1.89 0.24 0.18
 Jejunum
 Villus height, μm 401 448 420 18.4 0.37
 Crypt depth, μm 212b 233a 220b 6.8 0.04
 Villus height to crypt depth ratio 1.89b 1.97a 1.91ab 0.01 0.03
 Ileum
 Villus height, μm 357b 396a 384a 12.4 0.04
 Crypt depth, μm 211 217 213 5.6 0.37
 Villus height to crypt depth ratio 1.74b 1.85a 1.82ab 0.04 0.04
Intestinal Microflora (log 10 CFU/g of digesta)
 Ileum
 E. coli 4.37 4.14 4.25 0.18 0.85
 Lactobacillus 9.38 10.00 9.62 0.20 0.42
 Total aerobes 6.69a 6.60ab 6.43b 0.08 0.04
 Total anaerobes 9.36b 9.87ab 10.12a 0.23 0.03
 Cecum
 E. coli 3.37a 3.09b 3.22ab 0.12 0.04
 Lactobacillus 8.89b 9.47a 9.23a 0.14 0.03
 Total aerobes 3.88 3.77 3.49 0.44 0.63
 Total anaerobes 8.79 9.37 9.26 0.28 0.38
  1. Wu et al. [21].
  2. 1Kitasamycin and colistin sulfate.
  3. a,bWithin row, means followed by same or no letter do not differ (P>0.05).