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Table 2 Treatments applied to isolated growth plate proliferative chondrocytes: double stranded RNA (dsRNA) oligos to mediate post-transcriptional degradation of FGFR3 (siRNA FGFR3) and FGFR2 mRNA (siRNA FGFR2), scrambled dsRNA as control, 30 pM recombinant human FGF18, or 1 μM tri-iodothyronine (T3)

From: Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes

Treatment ScR siRNA T3
siRNA FGFR3 - + -
scrambled dsRNA + - -
thyroid hormone - - +
siRNA FGFR2 + + +
FGF18 + + +