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Table 5 Effects of in ovo leptin administration on hepatic expression of miRNAs predicted to target SREBP-1c and HMGCR in newly hatched chicks

From: In ovo leptin administration affects hepatic lipid metabolism and microRNA expression in newly hatched broiler chickens

Target Genes miRNA Control Leptin P value
SREBP-1c gga-miR-99a 0.98 ± 0.11 2.11 ± 0.42 0.024
  gga-miR-100 1.00 ± 0.11 2.03 ± 0.38 0.026
  gga-miR-183 1.05 ± 0.23 1.70 ± 0.23 0.070
  gga-miR-200b 0.97 ± 0.11 1.99 ± 0.40 0.033
  gga-miR-429 1.05 ± 0.08 2.04 ± 0.40 0.038
HMGCR gga-miR-15a 1.02 ± 0.12 1.84 ± 0.41 0.086
  gga-miR-15b 1.00 ± 0.10 1.24 ± 0.27 0.427
  gga-miR-16 1.03 ± 0.11 1.62 ± 0.36 0.147
  gga-miR-27b 1.02 ± 0.08 1.22 ± 0.23 0.416
  gga-miR-181a 0.96 ± 0.08 1.00 ± 0.18 0.663
  gga-miR-200a 1.02 ± 0.11 2.52 ± 0.64 0.045
  gga-miR-200b 0.97 ± 0.11 1.99 ± 0.40 0.033
  gga-miR-223 1.04 ± 0.07 1.39 ± 0.28 0.249
  gga-miR-429 1.05 ± 0.08 2.04 ± 0.40 0.038
  1. Values are presented as fold change relative to the control, expressed as means ± SEM (n = 12).