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Table 5 Effects of in ovo leptin administration on hepatic expression of miRNAs predicted to target SREBP-1c and HMGCR in newly hatched chicks

From: In ovo leptin administration affects hepatic lipid metabolism and microRNA expression in newly hatched broiler chickens

Target Genes

miRNA

Control

Leptin

P value

SREBP-1c

gga-miR-99a

0.98 ± 0.11

2.11 ± 0.42

0.024

 

gga-miR-100

1.00 ± 0.11

2.03 ± 0.38

0.026

 

gga-miR-183

1.05 ± 0.23

1.70 ± 0.23

0.070

 

gga-miR-200b

0.97 ± 0.11

1.99 ± 0.40

0.033

 

gga-miR-429

1.05 ± 0.08

2.04 ± 0.40

0.038

HMGCR

gga-miR-15a

1.02 ± 0.12

1.84 ± 0.41

0.086

 

gga-miR-15b

1.00 ± 0.10

1.24 ± 0.27

0.427

 

gga-miR-16

1.03 ± 0.11

1.62 ± 0.36

0.147

 

gga-miR-27b

1.02 ± 0.08

1.22 ± 0.23

0.416

 

gga-miR-181a

0.96 ± 0.08

1.00 ± 0.18

0.663

 

gga-miR-200a

1.02 ± 0.11

2.52 ± 0.64

0.045

 

gga-miR-200b

0.97 ± 0.11

1.99 ± 0.40

0.033

 

gga-miR-223

1.04 ± 0.07

1.39 ± 0.28

0.249

 

gga-miR-429

1.05 ± 0.08

2.04 ± 0.40

0.038

  1. Values are presented as fold change relative to the control, expressed as means ± SEM (n = 12).