Fig. 7

Propionate improved the wound healing of Caco-2 cells in vitro. A Representative phase contrast images of Caco-2 cells, scale bar = 1,000 px (1 px = 4.23 μm); B Quantification of average migration distance; C–F The relative gene expression of lgr5, ffar2, ffar3 and nlrc3 in Caco-2 cells (n = 3). Asterisk refers to the significant difference (ANOVA with Tukey’s test; ^*P < 0.05, ^**P < 0.01, ^***P < 0.001). CON, control; GOS, gossypol; SP, sodium propionate; lgr5, leucine-rich repeat-containing G protein-coupled receptor 5; ffar, free fatty acid receptor; nlrc3, NLR family CARD domain containing 3