Fig. 8From: Reorganization of 3D genome architecture provides insights into pathogenesis of early fatty liver disease in laying hensThe relationship analysis of folic acid nutritional target for FLS. A–D H3K27ac signal enrichment in the promoter regions and genome tracks of RNA-seq for MTHFR, MTRR, DNMT1 and CBS. E–H The detection of 5-MTHF and folic acid in the liver and serum. I Schematic diagram of folate/methionine cycles and their relationship with FLS. The enzyme expression framed with bule ellipses was down-regulated in hens with FLSBack to article page