Fig. 5

The interrelationship between gut microbiota and fecal metabolite profile by integrating fecal metagenomic and metabolome data. A The association between the α-diversity index of observed species and metabolite modules. Red represents a positive correlation and blue represents a negative correlation. Only the correlations with FDR < 0.05 were displayed. B The heatmap depicts the relationships between differential bacterial species, and fecal hormones and hormone related compounds. Spearman correlation coefficients were used. Red represents positive correlations and blue represents negative correlations. The stars in the grids represent the significance threshold: ⁺FDR < 0.05, ^*FDR < 0.01, ^**FDR < 0.001