Fig. 2

Co-abundance groups (CAGs) of bacterial species showing different abundances between normal and non-return sows and comparing the abundances of bacterial genes participating in the deconjugation of estrogen. A The network diagram of 7 CAGs showing different enrichments between normal return and non-return sows. The size of the nodes represents the abundance of bacterial species. The thickness of the connections between nodes indicates the weight of the correlation coefficient between species. Lines were drawn only when its correlation coefficient was greater than 0.5 and P < 0.05. The red lines represent a positive correlation and the gray lines represent a negative correlation. The colors of the nodes represent different CAGs. B Boxplots show the differential abundances of seven CAGs between two sow groups. Wilcoxon rank-sum test was performed for comparison analysis. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. C The comparisons of the abundances of β-glucuronidase, β-glucosidase, and hydroxysteroid dehydrogenases that participate in the deconjugation of estrogen. Wilcoxon rank-sum test was used for the comparison, ns, FDR > 0.05, ^*FDR < 0.05, ^***FDR < 0.001. Muribaculaceae, Prevotella, Prevotella copri, and Limosilactobacillus carried the K05349 gene that was annotated to β-glucosidase in their genomes