Fig. 6

Lipid metabolism pathways in the KEGG pathway and the rectal microbiome-bile acids relationship in the HS and HSB group. (n = 9). A Correlations between the hindgut bile acids classification with rectal microbiomes. B Significantly different KEGG pathways (Level 2) of gut microbiome between HS and HSB groups. C KEGG pathways (Level 3) with lipid metabolism of gut microbiome between HS and HSB groups. D The flow among the different classifications of bile acids. E Based on PICRUSt2 functional prediction. Gene copy numbers of 7α-hydroxysteroid dehydrogenase (7α-HSDH) and F Bile acid hydrolase (BSH) in HS and HSB group. HS means fed starch-rich diet, HSB means fed starch-rich diet supply 4 g/d bile acids for dairy goats every day. The differences in data (E) were tested by the Wilcon rank-sum test. The bars represent mean ± SEM. ^*P < 0.05. PBA Primary bile acid, SBA Secondary bile acid, FBA Free bile acid, CBA Conjugated bile acid, FPBA Free primary bile acid, FSBA Free secondary bile acid, CPBA Conjugated primary bile acid, CSBA Conjugated secondary bile acid, GPBA Glycine primary bile acid, GSBA Glycine secondary bile acid, TPBA Tauro-primary bile acid, TSBA Tauro-secondary bile acid