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Fig. 8 | Journal of Animal Science and Biotechnology

Fig. 8

From: Mechanisms underlying the role of endoplasmic reticulum stress in the placental injury and fetal growth restriction in an ovine gestation model

Fig. 8

Role of BPA treatment in ERS and autophagy levels of type A COT tissues of Hu ewes on d 130 of gestation. A ERS-associated gene levels. B Typical immunoblots for ERS-associated proteins. C ERS-associated protein levels. D Autophagy-associated gene levels. E Typical immunoblots showing autophagy-associated proteins. F Autophagy-associated protein levels. Data are presented as means ± SEM, n = 8. Means with no common letter are different (P < 0.05). ATF, activating transcription factor; BPA group, pregnant Hu ewes receiving Bisphenol A (5 mg/kg/d mixed sufficiently into corn oil) through subcutaneous injection; CON group, pregnant Hu ewes receiving corn oil only; COT, cotyledonary; CHOP10, C/EBP homologous protein 10; GRP78, glucose-regulated protein 78; LC3, microtubule-associated protein light chain 3; PINK1, PTEN induced putative kinase 1; ULK1, unc-51 like autophagy activating kinase 1

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Journal of Animal Science and Biotechnology

ISSN: 2049-1891