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Fig. 2 | Journal of Animal Science and Biotechnology

Fig. 2

From: Integrins and their potential roles in mammalian pregnancy

Fig. 2

The Saga of integrins: The integrin receptor (integrin) family. The integrin family can form at least 24 distinct pairings of its 18 α-subunits and 8 β-subunits. Integrins that bind to arginine-glycine-aspartic acid (RGD) sequences in ligands include αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, α5β1, α8β1, and αIIbβ3. Those that bind to laminin include α3β1, α6β1, α6β4 and α7β1. Integrins that bind the glycine-phenylalanine-hydroxyproline-glycine-glutamic acid-arginine (GFOGER) sequence in collagen include α1β1, α2β1, α10β1 and α11β1. Those that are leukocyte-specific receptors include α4β1, αLβ2, αMβ2, αDβ2 and αXβ2

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