Fig. 4From: Genome-wide DNA methylation and transcriptome analyses reveal the key gene for wool type variation in sheepAnalysis of differentially expressed genes at different developmental stages of skin tissue between coarse and fine wool breeds using transcriptome public data. A RNA-seq data analysis workflow of coarse and fine wool breeds. (I) Fastq data check and quality control. (II) Reads alignment and count. (III) Gene differential expression analysis. B PCA analysis of all expressed genes for sheep of different breeds and different periods. C The bar-plot of TPM mean for DNMT3A, ARID4A, BRCA1, CTCF gene between coarse and fine wool breeds at three stages. *0.01 < P < 0.05, ***P < 0.001. D The bar-plot of TPM mean for METTL3, METTL14, FTO, ALKBH5, YTHDF1, YTHDF2 and HNRNPA2B1 gene between coarse and fine wool breed at three stages. *0.01 < P < 0.05, ***P < 0.001. E The key epigenetic regulators expression in ALC wool lamb skinBack to article page