Figure 1

FGFR3 siRNA and T ₃ effects on FGFR3 mRNA and protein. A) FGFR3 mRNA (femtogram) at 3 (siRNA 3d) and 7 (siRNA 7d) days post siRNA transfection; B) FGFR3 mRNA as a percentage of untreated control cells in response to T₃ treatment at 3 and 7 days post exposure. Data are presented as mean ± SEM. An asterisk (*) denotes means differed from control at p < 0.05; † denotes means differed from control at p < 0.1. C) FGFR3 protein levels at 3 days post siRNA transfection for FGFR3 siRNA (lane 1), ScR control treated chondrocytes (lane 2), and T₃ treated chondrocytes. The blot image is representative of the replicate blots performed and greater amounts of protein were loaded for the FGFR3 siRNA lane to ensure detectable signal.